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Hemoglobin is a big protein molecule made up of four connected glob-shaped molecules called globulin chains; two are alpha chains and two are beta Sexy Jerusalem at 3. People with these differences in their blood cells live normally. Hemolytic anemia will occur as a result of the burst of the sickle shape red blood cells when passing through blood vessels due to the rigid sickle cell structure. Most hemoglobin abnormalities are from one or a few amino acid changes in their protein contents, resulting from one or a few DNA base pair changes also called mutation in the genes.

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Ruoming Fan1and Yu Bai2 1St. Most hemoglobin abnormalities are from one or a few amino acid changes in their protein contents, resulting from one or a few DNA base pair changes also called mutation in the genes.

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